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Selenium and Vitamin E Cancer Prevention Trial : ウィキペディア英語版 | Selenium and Vitamin E Cancer Prevention Trial The Selenium and Vitamin E Cancer Prevention Trial, or SELECT, was a clinical trial conducted with the goal of determining whether vitamin E and selenium supplements could prevent prostate cancer.〔(Selenium and Vitamin E Cancer Prevention Trial Q&A )〕 Enrollment for the trial began in 2001 and ended in 2004.〔 It cost approximately $114 million to conduct and was performed at over 400 different research centers. It was primarily funded by the National Cancer Institute (NCI) and was carried out by SWOG.〔 It was stopped early because the supplements did not show any benefit in preventing prostate cancer. Subsequent research based on the trial has generally found that selenium and vitamin E do not prevent prostate cancer. ==Methodology== The study followed over 35,000 men in the United States, Puerto Rico, and Canada, who were assigned randomly to receive either both a selenium and vitamin E supplement, selenium and placebo, vitamin E and placebo, or two placebos. It was one of the largest cancer prevention trials ever conducted, and was described by the NCI as "the largest-ever prostate cancer prevention study."〔(Largest-Ever Prostate Cancer Prevention Trial Opens: 32,000 Men Sought to Test Vitamin E and Selenium )〕 The study was originally planned to last for twelve years after enrollment began.〔 However, it was stopped early in 2008 because no protective effect of supplementation on prostate cancer risk was found, and because the results suggested that vitamin E might increase the risk.〔 About 17,000 participants from the original SELECT completed an additional four years of a Centralized Follow-Up from 2010 until May 31, 2014, when SELECT closed.〔(SELECT )〕 The follow-up involved sending questionnaires to participants annually, which they could also fill out online.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Selenium and Vitamin E Cancer Prevention Trial」の詳細全文を読む
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